Fasting-Like Diet Lowers Risk Factors for Disease, Reduces Biological Age

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Cycles of a diet that mimics fasting reduce signs of immune system aging as well as insulin resistance and liver fat in humans, resulting in a lower biological age, according to a new USC Leonard Davis School of Gerontology-led study.

The study, which appears in Nature Communications on February 20, 2024, adds to the body of evidence supporting the beneficial effects of the fasting-mimicking diet (FMD). The FMD is a 5-day diet high in unsaturated fats and low in overall calories, protein, and carbohydrates and is designed to mimic the effects of a water-only fast while still providing necessary nutrients and making it much easier for people to complete the fast. The diet was developed by the laboratory of USC Leonard Davis School Professor Valter Longo, the senior author of the new study.

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